Neuro-Adrenal Expanded Test  

The Adrenal Glands
The adrenals are two small glands, each weighing 3 to 5 grams, that are located above the kidneys. The adrenals have one of the highest rates of blood flow per gram of tissue, and the highest content of Vitamin C per gram of any tissue in the body. 

Each adrenal gland is composed of two separate functional entities. The outer zone, or cortex, accounts for 80% to 90% of the gland, and secretes adrenal steroids (Cortisol, DHEA(S) and Aldosterone). The inner zone, or medulla, comprises 10% to 20% of the gland, and secretes the catecholamines adrenaline and nor-adrenaline. Cortisol, DHEA and adrenaline are the three main adrenal stress hormones. 

The Adrenal Rhythm & Its Importance
The human adrenal gland does not secrete its steroid hormones at a constant level throughout the day. The hormones are actually released in a cycle with the highest value in the morning and the lowest value at night. This is easily understood by looking at Figure 1. This 24-hour cycle is called the circadian rhythm. An abnormal adrenal rhythm can influence many functions of the body, some of which are listed below. 

Neurotransmitters 

Neurotransmitters are chemicals produced in various parts of the body (intestines, glands, organs, and the brain) that aid in communication in the brain and body affecting mood and multiple other functions.   

This test can help determine imbalances contributing to: 

• Depression   
•  Anxiety,   
•  Panic Attacks   
•  Insomnia   
•  Cognitve Disorders   
•  ADD/ADHD   
•  Fibromyalgia   
•  Chronic Pain   
•  Neurotoxicity   
•  Memory impairment  
• Migraine Headaches   
• Adrenal Fatigue  
• Obsessions  Compulsions   
•  Mood Swings  
• Weight Issues  

This expanded profile includes additional neurotransmitter metabolites, DOPAC and 5-HIAA, to assist in assessing serotonin and dopamine activity. It also includes the addition of the amino acid taurine, which is useful in confirming the extent of the stress response. Taurine re-assessment also provides confirmation of patient therapy utilization.  

This profile includes the following tests: 

Epinephrine
Norepinephrine
Dopamine
DOPAC
Serotonin
5-HIAA
Glycine
Taurine
GABA
Glutamate
PEA
Histamine
DHEA
Cortisol X 4